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| Product Name | TXNRD1, 161-647aa, Human, His tag, E Coli (Bioactivity Validated) |
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| Description | MW: 55.7 kDa (508aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotide-disulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS a |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Thioredoxin reductase 1; GRIM-12; MGC9145; TR; TR1; TRXR1; TXNR; Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein; GRIM 12; GRIM12; KDRF; KM 102 derived reductase like factor; MGC9145; Oxidoreductase; Thioredoxin reductase 1; Thioredoxin reductase 1 cytoplasmic; Thioredoxin reductase GRIM 12; Thioredoxin reductase TR1; TR 1; TRXR 1; TXNRD 1.] |
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| Gene, Accession, CAS # | TXNRD1, Gene ID: 7296, Accession: NP_001087240 |
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| Catalog # | MBS203663 |
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| Order / More Info | TXNRD1, 161-647aa, Human, His tag, E Coli (Bioactivity Validated) from MYBIOSOURCE INC. |
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| Product Specific References | Ma X. et al. (2002) J Biol Chem. 277 (25):22460-8.; Javvadi P. (2010) Cancer Res. 70 (5):1941-50.; |
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