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| Product Name | Methylcarbamyl PAF C-8 |
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| Description | Purity >98%. Methylcarbamyl PAF C-8 is the C-8 analog of Methylcarbamyl PAF C-16. Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. It is nearly equipotent with PAF C-16 in its ability to induce platelet aggregation both in isolated platelets and in platelet-rich plasma. In NRK-49 cells overexpressing the PAF receptor, both PAF C-16 and methylcarbamyl PAF C-16 cause the induction of c-myc, c-fos, and the activation of mitogen-activated protein kinase. Methylcarbamyl PAF C-16 induces G1 phase cell cycle arrest, suggesting a potential role for PAF in the inhibition of oncogenic transformation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-O-octyl-2-O-(N-methylcarbamoyl)-sn -glyceryl-3-phosphorylcholine |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H8654 |
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| Order / More Info | Methylcarbamyl PAF C-8 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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