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| Product Name | 1-Aminobenzotriazole |
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| Description | Purity >98%. 1-aminobenzotriazole (ABT) is a non-specific cytochrome P450 (CYP) inhibitor. It does not appear to affect other enzymes, including UDP-glucuronosyltransferases. ABT acts as a CYP suicide substrate, producing maximal destruction of hepatic and renal microsome CYP protein in vitro at 10 mM. It is effective in vivo, significantly reducing CYP content in both liver and kidney in rats within two hours. The effects of ABT on CYP activity is time-dependent, with significant shift in IC50 values with preincubation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1H-benzotriazol-1-amine, 1-Benzotriazolylamine, 3-Aminobenzotriazole, ABT, NSC 114498, NSC 656987 |
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| Gene, Accession, CAS # | CAS: 1614-12-6 |
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| Catalog # | LS-H5880 |
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| Order / More Info | 1-Aminobenzotriazole from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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