| 产品详情 |
| Edit |   |
|---|
| Product Name | ATP-Citrate Lyase, NT GST-Tag, Recombinant, Human |
|---|
| Description | Purity ~90% by SDS-PAGE. ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Source: Recombinant corresponding to full length human ATP citrate lyase with N-terminal GST tag expressed in baculovirus expression system (NM_001096). Specific Activity: ~400pmole/min/ug. A Assay Condition: 25ul of ACLY reaction is conducted in a buffer containing 40mM Tris, pH 8.0, 10mM magesium chloride, 2mM DTT, 2mM potassium citrate, 0.1mM CoA, 6-100ng human ACLY at 30°C for 60 minute. Enzyme activi |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | ATP-Citrate Lyase, NT GST-Tag, Recombinant, Human (ACLY, ATP Citrate (pro-S) Lyase, ATP Citrate Synthase, Citrate Cleavage Enzyme, EC 2.3.3.8) |
|---|
| Gene, Accession, CAS # | Accession: NM_001096 |
|---|
| Catalog # | A4001-35R |
|---|
| Price | |
|---|
| Order / More Info | ATP-Citrate Lyase, NT GST-Tag, Recombinant, Human from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|