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| Product Name | SET, Recombinant, Human, aa1-290, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). SET inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. Source: Recombinant protein corresponding to human SET, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~35.9kD (313aa) (MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAPKRQS PLPPQKKKPR PPPALGPEET SASAGLPKKG EKEQQEAIEH IDEVQNEIDR LNEQASEEIL KVEQKYNKLR QPFFQKRSEL IAKIPNFWVT TFVNHPQVSA LLGEEDEEAL HYLTRVEVTE FEDIKSGYRI DFYFDENPYF ENKVLSKEFH LNESGDPSSK STEIKWKSGK DLTKRSSQTQ N |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SET, Recombinant, Human, aa1-290, His-Tag (Protein SET Isoform 1, 2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137206 |
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| Order / More Info | SET, Recombinant, Human, aa1-290, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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