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Antigenic Specificity | Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (aa 6-20), (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The catalytic subunit of human protein phosphatase 2A(PPP2CA) encodes a 309-amino acid polypeptide.It is localized to chromosome 5. The gene(approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue(Leu309) of protein serine/threonine phosphatase 2A catalytic subunit(PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases. |
Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human PP2A(6-20aa FTKELDQWIEQLNEC), identical to the related rat and mouse sequences. |
Other Names | pp2ac|Ppp2ca|zgc:110641|PP2A|R75353|PP2Ac|PP2CA|PP2Calpha|RP-C|Pp2a1|PPP2CA |
Gene, Accession # | Gene ID: 5515,24672 |
Catalog # | ABIN343439 |
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Order / More Info | Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (aa 6-20), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 1846293, 2837763, 10191253, 15247211 |
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