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| Product Name | BD1, Human (beta Defensin-1) |
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| Description | Purified ≥ 95% by HPLC. Synthesized from 68 aa precursor (mature peptide 33-68 aa). The sequence is: DHY NCV SSG GQC LYS ACP IFT KIQ GTC YRG KAK CCK, 36 aa; mol wt 3.935kD; The full length HBD-1 was synthesized and disulfides were formed in their natural orientation). The peptide has been purified by HPLC to >95% purity. Antimicrobial peptides are a common mechanism of host defense utilized by a variety of species, from insects to humans. Defensins are a large family of broad-spectrum antimicrobial peptides, identified originally in leukocytes of rabbits and humans. Defensins, cationic/polar peptides (30-35 aa; 3-4kD), are distinguished by a conserved tri-disulfides and a largely b-Sheet structure. Defensins, expressed at the cell surface, have been hypothesized to function as a biochemical barrier against microbial infection by inhibiting colonization of the epithelium by wide range of pathogenic microorganisms. In leukocytes, these peptides are stored in cytoplasmic granules and are |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | B0899-02 |
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| Price | |
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| Order / More Info | BD1, Human (beta Defensin-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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