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| Product Name | HIV-2 gp36, Recombinant, His-Tag (Human Immunodeficiency Virus Type 2) |
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| Description | Purity ~95% (HPLC, SDS-PAGE). HIV-1 and HIV-2 appear to package their RNA differently. HIV-1 binds to any appropriate RNA whereas HIV-2 preferentially binds to mRNA which creates the Gag protein itself. This means that HIV-1 is better able to mutate. HIV-2 is transmitted in the same ways as HIV-1: Through exposure to bodily fluids such as blood, semen, tears and vaginal fluids. Immunodeficiency develops more slowly with HIV-2. HIV-2 is less infectious in the early stages of the virus than with HIV-1. The infectiousness of HIV-2 increases as the virus progresses. Major differences include reduced pathogenicity of HIV-2 relative to HIV-1, enhanced immune control of HIV-2 infection and often some degree of CD4- independence. Despite considerable sequence and phenotypic differences between HIV-1 and 2 envelopes, structurally they are quite similar. Both membrane- anchored proteins eventually form the 6-helix bundles from the N-terminal and C-terminal regions of the ectodomain, which is com |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209006 |
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| Order / More Info | HIV-2 gp36, Recombinant, His-Tag (Human Immunodeficiency Virus Type 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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