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| Product Name | HMGCL, Recombinant, Human, aa28-325, His-Tag (Hydroxymethylglutaryl-CoA Lyase, Mitochondrial Isoform 1, HL) |
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| Description | Purity ~90% (SDS-PAGE). HMGCL, also known as hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1, is a mitochondrial matrix protein that belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Multiple isoforms of the proteins are known due to alternative splicing. The major isoform (isoform 1) is most highly expressed in the liver whereas isoform 2 is found in energy-demanding tissues including the brain, heart, and skeletal muscle. Source: Recombinant protein corresponding to aa28-325 from human HMGCL, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~32.5kD (305aa), 28-40kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_000182 |
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| Catalog # | 377834 |
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| Order / More Info | HMGCL, Recombinant, Human, aa28-325, His-Tag (Hydroxymethylglutaryl-CoA Lyase, Mitochondrial Isoform 1, HL) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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