| 产品详情 |
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| Product Name | Recombinant Human B-cell lymphoma/leukemia 10 |
| Description | 1-233aa; Full Length. MW: 42.2kD. Purity >90% as determined by SDS-PAGE. Involved in adaptive immune response. Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1. |
| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [B-cell CLL/lymphoma 10; hCLAPCED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10; mE10] |
| Gene, Accession, CAS # | BCL10, Gene ID: 8915, Accession: NP_003912.1 |
| Catalog # | MBS1164977 |
| Price | |
| Order / More Info | Recombinant Human B-cell lymphoma/leukemia 10 from MYBIOSOURCE INC. |
| Product Specific References | Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types.Willis T.G., Jadayel D.M., Du M.-Q., Peng H., Perry A.R., Abdul-Rauf M., Price H., Karran L., Majekodunmi O., Wlodarska I., Pan L., Crook T., Hamoudi R., Isaacson P., Dyer M.J.S.Cell 96:35-45(1999) CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10.Koseki T., Inohara N., Chen S., Carrio R., Merino J., Hottiger M.O., Nabel G. |
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