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| Product Name | SGC707 |
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| Description | Purity >98%. Protein arginine N-methyltransferase 3 (PRMT3,) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets. Developed by the Structural Genomics Consortium (SGC), SGC707 avidly binds PRMT3 (Kd = 50 nM by isothermal titration calorimetry) and inhibits the methylation of histones in cells with an IC50 value below 1 µM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-urea |
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| Gene, Accession, CAS # | CAS: 1687736-54-4 |
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| Catalog # | LS-H9909 |
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| Order / More Info | SGC707 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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