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| Product Name | Nectin 3, Recombinant, Human (Poliovirus Receptor-related Protein 3, PRR3) |
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| Description | Purity ≥ 95%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain.Endotoxin: ≤ 1EU/1ug. Nectins are a small family of Ca++-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions (1, 2, 3, 4). The Nectin family has at least four members (Nectin-1-4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1γ), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus (1). Nectin-3 (also PRR3, CD113 and PVRL3) is an 83kD, type I TM glycoprotein. Its precursor is 549 amino acids (aa) in length. It contains an extended signal sequence of 57 aa, an extracellular domain (ECD) of 347 aa, a transmembrane segment of 21 aa (aa 405-425), and a cytoplasmic region of 124 amino acids. The ECD shows three Ig-like |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_056295 |
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| Catalog # | N0571-55H |
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| Order / More Info | Nectin 3, Recombinant, Human (Poliovirus Receptor-related Protein 3, PRR3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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