| 产品详情 |
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| Product Name | NEDD8, 1-76aa, Human, His tag, E Coli |
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| Description | MW: 12.8 kDa (113 aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. NEDD8 belongs to the ubiquitin family and human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The NEDD8 system is essential for the regulation of protein degradation pathways involved in cell cycle progression, morphogenesis and tumorigenesis. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and ot |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Neural precursor cell expressed developmentally down-regulated 8; ubiquitin-like protein Nedd8; Neddylin; Neural precursor cell expressed; developmentally down-regulated 8 MGC104393; MGC125896; MGC125897; NED8; 0NEDD 8; Neddylin; Neural precursor cell expressed developmentally down regulated 8; Neural precursor cell expressed developmentally down regulated gene 8; Rub1; ubiquitin like protein Nedd 8; ubiquitin like protein Nedd8.] |
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| Gene, Accession, CAS # | NEDD8, Gene ID: 4738, Accession: NP_006147 |
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| Catalog # | MBS203213 |
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| Order / More Info | NEDD8, 1-76aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Wu K., et al. (2002) J Biol Chem. 277 (1): 516-27; Hori T., et al. (1999) Oncogene. 18 (48): 6829-34; |
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