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| Product Name | sFas Receptor, Recombinant, Human |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively.Binding of FasL to Fas triggers apoptosis in Fas-bearing cells.The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms.These active caspases then cleave various cellular substrates leading to the eventual cell death.sFasR is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor that serves as a sink for FasL.The full length Fas (receptor) is a 319 amino acid type I transmembrane protein, which contains a 157 amino acid extracellular domain, a 17 amino acid transmembrane domain, and 145 amino acid cytoplasmic domain.Recombinant human soluble Fas (sFas Receptor) is a 157 amino acid polypeptide (17.6kD) corresponding to the TNFR homologous cysteine rich extracellular domain Fas. Biological Activity: |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | sFas Receptor, Recombinant, Human (soluble Fas receptor (sFasR), TNFRSF6, CD95, Apo I, Fas Antigen) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143501 |
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| Order / More Info | sFas Receptor, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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