| 产品名称 |
sFas Receptor, Recombinant, Human (Soluble Fas Receptor, sFasR, TNFRSF6, CD95, Apo I, Fas Antigen) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | sFas Receptor, Recombinant, Human (Soluble Fas Receptor, sFasR, TNFRSF6, CD95, Apo I, Fas Antigen) |
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| Description | Purity ~98% (SDS-PAGE). Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL induced apoptosis by acting as a decoy receptor that serves as a sink for FasL. The full length Fas (receptor) is a 319aa type I transmembrane protein, which contains a 157aa extracellular domain, a 17aa transmembrane domain, and 145aa cytoplasmic domain. Recombinant human soluble Fas (sFas Receptor) is a 157aa polypeptide corresponding to the TNFR homologous cysteine rich extracellular domain Fas. Source: Recombinant protein corresponding to 157aa from human soluble Fas Receptor, expresse |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | soluble Fas receptor (sFasR), TNFRSF6, CD95, Apo I, Fas Antigen |
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| Gene, Accession, CAS # | FASL, SwissProt: P25445 |
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| Catalog # | 220261 |
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| Order / More Info | sFas Receptor, Recombinant, Human (Soluble Fas Receptor, sFasR, TNFRSF6, CD95, Apo I, Fas Antigen) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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