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| Product Name | SF3B14, 1-125aa, Human, His tag, E Coli |
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| Description | MW: 16.7 kDa (145aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. SF3B14, also known as SAP14, is a 125 amino acid nuclear protein that is a component of the splicing factor 3b complex. Splicing factor 3b associates with both the u2 and u11/u12 small nuclear ribonucleoprotein complexes (u2 snRNP) of spliceosomes. Required for the splicing of pre-mRNA, SF3B14 enters the spliceosome and associates with the pre-mRNA branch site facilitating the interaction of snRNP with the branch sites of u2 |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Splicing factor 3B 14 kDa subunit; Splicing factor 3B; 14 kDa subunit; CGI-110; HSPC175; Ht006; P14; SAP14; SF3B14a] |
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| Gene, Accession, CAS # | SF3B14, Gene ID: 51639, Accession: NP_057131 |
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| Catalog # | MBS203984 |
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| Order / More Info | SF3B14, 1-125aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Golas MM., et al. (2003) Science. 300 (5621):980-4.; Will CL., et al. (2002) EMBO J. 21 (18):4978-88. |
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