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Antigenic Specificity | Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (aa 38-55), (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TNFRSF1B(Tumor Necrosis Factor Receptor Subfamily Member 1B), also known as TNFR2 or TNFBR, is a protein that in humans is encoded by the TNFRSF1B gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1A. By linkage analysis, Santee and Owen Schaub(1996) confirmed the mapping of the TNFR2 gene to 1p36.3-p36.2. TNFBR(TNFR75) is the larger of the 2 TNF receptors. It is present on many cell types, especially those of myeloid origin, and is strongly expressed on stimulated T and B lymphocytes. Beltinger et al.(1996) noted that TNFR2 is the main TNF receptor found on circulating T cells and is the major mediator of autoregulatory apoptosis in CD8+ cells. TNFR2 may act with TNFR1 to kill nonlymphoid cells. |
Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of mouse TNF Receptor II(38-55aa YECQISQEYYDRKAQMCC), different from the related rat sequence by three amino acids. |
Other Names | MGC83471|LOC100218184|TRAF2|TANK|TNF-RII/TNFRSF1B|TNFRSF1B|CD120b|TBPII|TNF-R-II|TNF-R75|TNFBR|TNFR1B|TNFR2|TNFR80|p75|p75TNFR|TNF-R2|TNF-alphaR2|TNFRII|TNFalpha-R2|Tnfr-1|Tnfr2|TNFR-II |
Gene, Accession # | Gene ID: 21938,156767 |
Catalog # | ABIN1673457 |
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Order / More Info | Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (aa 38-55), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 8661109, 8702885 |
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