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Antigenic Specificity | CD86 Molecule (CD86) (aa 66-80), (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD86 is officially called Cluster of Differentiation 86, also known as B7-2. Being a member of the immunoglobulin superfamily, it is a protein expressed on antigen-presenting cells. The CD86 gene is mapped to human chromosome 3q21. The smallest transcript, 828 bp, which the authors termed CD86deltaTM, has a deletion from nucleotide 686 to nucleotide 829(i.e., exon 6) and encodes a 275-amino acid protein. CD86deltaTM enhances proliferation and cytokine production by both naive and memory T cells, providing costimulatory signals necessary for T cell activation and survival. |
Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of mouse CD86(66-80aa YEHYLGTEKLDSVNA), different from the related rat sequence by two amino acids. |
Other Names | B7-2|B7|B7.2|B70|CLS1|Cd28l2|ETC-1|Ly-58|Ly58|MB7|MB7-2|TS/A-2|CD28LG2|LAB72 |
Gene, Accession # | Gene ID: 12524 |
Catalog # | ABIN1706101 |
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Order / More Info | CD86 Molecule (CD86) (aa 66-80), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 22806934, 17448455, 7513726, 7541777, 7694363 |
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