| 产品详情 |
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| Antigenic Specificity | Human CTLA-4 |
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| Clone | 22I8M28 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | FC, ICC, IF |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human CTLA-4 monoclonal antibody for FC, ICC, IF,. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. |
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| Immunogen | Protein corresponding to human CTLA4 (aa186-223) |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 1493, UniProt: P16410 |
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| Catalog # | CABT-L1256 |
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| Price | |
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| Order / More Info | Human CTLA-4 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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