| 产品详情 |
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| Antigenic Specificity | CD45RA Or A/B |
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| Clone | OX-33 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG1 |
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| Format | Protein G purified |
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| Size | 250 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The rat CD45 antigen (Leukocyte Common Antigen (L-CA)) has been shown to exist in different forms on different lymphoid cell types. CD45 on thymocytes shows one main band at 180 kDa, T cells show 4 bands at 180, 190, 200 and 220 kDa. ABIN133310detects a subfraction of the 240 kDa rat CD45 band found only on B lymphocytes. This monoclonal antibody is of particular use in the investigation of the molecular and antigenic heterogeneity of rat L-CA, especially when used in conjunction with other OX antibodies. Four mouse monoclonal antibodies (MRC OX 1, 28, 29 and 30) react with all molecular forms of L-CA and fall into two sets that are non-competitive in binding to L-CA (MRC OX 1, 28, 29 and 30). The antigenic determinants seen by all these antibodies are lost when L-CA is reduced and alkylated. Three antibodies (MRC OX 22, 31, and 32) react selectively with B cells, T cytotoxic cells and about two thirds of T helper cells. OX 22 and OX 31 compete for binding but are non- competitive with OX 32. All of these antibodies bind to a sub-fraction of the 190, 200 and 220 kDa forms of T cell L-CA but not at all to the 180 kDa form of T cells or thymocytes. This clone works in flow cytometry and with frozen and paraffin sections (2). |
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| Immunogen | Rat purified spleen L-CA . Fusion Partner: NSO/U . Donor: BALB/c spleen |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN133310 |
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| Price | |
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| Order / More Info | CD45RA Or A/B Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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