产品详情 |
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Antigenic Specificity | CD45 |
Clone | HI30 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | fluorescein (FITC) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal FITC conjugated antibody to detect CD45 in human samples. CD45, a transmembrane multifunctional glycoprotein, is a member of Type I receptor-linked PTPase family and is expressed as multiple isoforms due to alternative splicing. Expression of these isoforms is highly regulated and shift in this expression determines T-cell activation. CD45RB consists of exon B and is predominantly expressed in naive T-cells secreting IL-2. Its expression is low in primed/memory T cells, cells that express Th2 cytokines such as IL-4 and IL-10 and population of T-cells with regulatory function. Immunotherapy with CD45RB antibody is being widely studied in transplantation and vaccination. CD45 antibodies are commonly used to identify tumors of |
Immunogen | Human CD45 |
Other Names | CD45 |
Gene, Accession # | Gene ID: 5788, Accession: P08575 |
Catalog # | 6958-25 |
Price | |
Order / More Info | CD45 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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