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| Product Name | CDKN1B, 1-198aa, Human, His tag, E Coli |
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| Description | MW: 24.2 kDa (218aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher). Purity >90% by SDS-PAGE. CDKN1B, also known as cyclin-dependent kinase inhibitor 1B, belongs to the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. This protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. It is often referred to as a cell cycle inhibitor protein because its major function is to |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Cyclin-dependent kinase inhibitor 1B; CDKN4; KIP1; MEN1B; MEN4; P27KIP1] |
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| Gene, Accession, CAS # | CDKN1B, Gene ID: 1027, Accession: NP_004055 |
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| Catalog # | MBS204754 |
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| Order / More Info | CDKN1B, 1-198aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Ishida N., et al. (2000) J. Biol. Chem. 275:25146-25154; Viglietto G., et al. (2002) Nat. Med. 8:1136-1144 |
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