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| Product Name | Fibroblast Growth Factor Receptor 2, Recombinant, Human |
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| Description | Purity ~90% (RP-HPLC, SDS-PAGE). Fibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family if type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1 to -4 are known. Multiple forms of FGFR-1 to -3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGFR-1 and -2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform. Only the alpha isoform has been identified for FGFR-3 and FGFR-4. Additional splicing events for FGFR-1 to -3, involving the C-terminal half of the IgIII |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Fibroblast Growth Factor Receptor 2, Recombinant, Human (Keratinocyte Growth Factor Receptor 2, CD332, FGFR2) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208896 |
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| Order / More Info | Fibroblast Growth Factor Receptor 2, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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