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| Product Name | Human BAFF/BLYS (CD257) Recombinant |
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| Description | MW: 31,223 Da. Purity >95%, as determined by SDS-PAGE and HPLC. The B cell-activating factor from the TNF family (BAFF), is emerging as an important regulator of B cell and T cell responses. BAFF was originally identified as a factor responsible for B cell survival and maturation.BAFF binds to several receptors. These include transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), BAFF-R (BR3), and B cell maturation Ag (BCMA). BAFF-R appears to be particularly imp |
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| Size | 0.005 mg, 0.02 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Human BAFF/BLYS Recombinant; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; baff; baffr; TNFRSF13C] |
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| Gene, Accession, CAS # | BAFF, Gene ID: 10673, Accession: NP_001139117.1 |
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| Catalog # | MBS553249 |
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| Order / More Info | Human BAFF/BLYS (CD257) Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • soluble BAFF levels inversely correlate with peripheral b cell numbers and the expression of BAFF receptors .J. Immunol., Jan 2012; 188: 497 - 503. • BAFF/april inhibition decreases selection of naive but not antigen-induced autoreactive b cells in murine systemic lupus erythematosus .J. Immunol., Dec 2011; 187: 6571 - 6580. • increased levels of BAFF in patients with systemic lupus erythematosus are associated with acute-phase reactants, independent of BAFF genetics: a case-con |
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