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| Product Name | NKIRAS1, Recombinant, Human, aa1-192, His-Tag (NF-kappa-B inhibitor-interacting Ras-like protein 1) |
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| Description | Purity ~95% (SDS-PAGE). NKIRAS1, also known as NF-kappa-B inhibitor-interacting Ras-like protein 1, belongs to the small GTPase superfamily. NKIRAS1 is atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. It may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Source: Recombinant protein corresponding to aa1-192 of human NKIRAS1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~23.8kD AA |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_065078 |
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| Catalog # | 350119 |
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| Order / More Info | NKIRAS1, Recombinant, Human, aa1-192, His-Tag (NF-kappa-B inhibitor-interacting Ras-like protein 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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