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| Product Name | NKp46, Natural Cytotoxicity Receptor, Recombinant, Human |
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| Description | Purity ≥ 95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel. A natural cytotoxicity receptor (NCR) NKp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors(NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. The three known NCRs include NKp46 and NKp30,which are expressed on circulating NKcells, and NKp44,which is expressed only on activating NK cells. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. NKp46 has two extracellular Ig-like domains followed by a ~40 residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. The extracellular Ig-like domain of NKp46( 22-255aa) purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NKp46, Natural Cytotoxicity Receptor, Recombinant, Human (NCR NKp46, Natural Killer Cell Activating Receptor NKp46) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N2835A |
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| Order / More Info | NKp46, Natural Cytotoxicity Receptor, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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