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| Product Name | ProNGF, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE, HPLC). The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystine knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration. Source: Recombinant protein corresponding to 222aa from human proNGF, expressed in E.coli. Molecular Weight: ~25kD Endotoxin: <0.1ng/ug (1IEU/ug) |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ProNGF, Recombinant, Human (Beta-Nerve Growth Factor, Beta-NGF, Ngf, Ngfb, HSAN5, MGC161426, MGC161428) |
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| Gene, Accession, CAS # | SwissProt: P01138 |
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| Catalog # | 169728 |
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| Price | |
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| Order / More Info | ProNGF, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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