| 产品详情 |
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| Product Name | Proopiomelanocortin |
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| Description | Purity ~95%. Purified by HPLC. Pro-opiomelanocortin (POMC) is a precursor polypeptide with 241 amino acid residues. It is synthesized by corticotrope cells of the anterior pituitary gland, melanotrope cells of the intermediate lobe of the pituitary gland, about 3000 neurons in the arcuate nucleus of the hypothalamus, and smaller populations of neurons in the dorsomedial hypothalamus and brainstem. The large molecule of POMC is the source of several important biologically active substances. POMC can be cleaved enzymatically into the following peptides: adrenocorticotrophic hormone (ACTH) and gamma LPH in the anterior pituitary gland CLIP, gamma LPH, gamma MSH and beta-endorphin in the intermediate lobe gamma-MSH met-enkephalin Each of these peptides is packaged in large dense-core vesicles that are released from the cells by exocytosis in response to appropriate stimulation. gamma MSH produced by neurons in the arcuate nucleus has important roles in the regulation of appetite and sexual |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Proopiomelanocortin (POMC, Adrenocorticotropin, beta Lipotropin, alpha (beta) Melanocyte Stimulating Hormone, ACTH, CLIP, Corticotropin-lipotropin precursor, LPH, MSH, NPP, POC, Pro-opiomelanocortin) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P9025-10A |
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| Order / More Info | Proopiomelanocortin from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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