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| Product Name | Recombinant Human Secreted Ly-6/uPAR-related protein 1 (SLURP1) |
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| Description | 23-103aa. MW: 8.9 kDa. Purity >85% as determined by SDS-PAGE. Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [ARS component B; ARS (component B)-81/S; Anti-neoplastic urinary protein] |
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| Gene, Accession, CAS # | SLURP1, Gene ID: 57152, Accession: NP_065160.1 |
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| Catalog # | MBS7110890 |
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| Price | |
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| Order / More Info | Recombinant Human Secreted Ly-6/uPAR-related protein 1 (SLURP1) from MYBIOSOURCE INC. |
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| Product Specific References | Partial N-terminal amino acid sequence of the anti-neoplastic urinary protein (ANUP) and the anti-tumour effect of the N-terminal nonapeptide of the unique cytokine present in human granulocytes. Ridge R.J., Sloane N.H.Cytokine 8:1-5 (1996) |
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