| 产品详情 |
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| Product Name | Rebastinib |
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| Description | Rebastinib shows the selectivity for growth inhibition of Bcr-Abl-positive cells by its marked inhibition of CML cell lines compared to non-CML leukemia lines. Rebastinib (DCC-2036) is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1. Molecular Formula: C30H28FN7O3 Solubility: Methanol (Slightly) Molecular Weight: 553.59 |
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| Size | 1mg, 2.5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 464554 |
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| Order / More Info | Rebastinib from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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