| 产品详情 |
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| Product Name | DAPT |
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| Description | Purity ≥98% (NMR). Cell permeable gamma-secretase inhibitor (IC50 = 115nM for total beta-amyloid, IC50 = 200nM for beta-amyloid 1-42). Reduces Abeta levels in vivo. Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD). Does not inhibit persenilinase. Notch processing inhibitor. Enhances neuronal differentiation independent of sonic hedgehog (Shh) signaling. CDK5 activity inhibitor. Apoptosis enhancer. Synonyms: N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine tert.butyl ester |
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| Size | 5mg, 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (S)-Tert-butyl 2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate; N-S-phenylglycine tert.butyl ester; GSI-IX; Secretase, gamma Inhibitor IX |
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| Gene, Accession, CAS # | CAS: 208255-80-5 |
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| Catalog # | 44723 |
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| Order / More Info | DAPT from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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