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| Product Name | Acid Sensitive Ion Channel 2b, Rat (ASIC2B, MDEG2, Mammalian Degenerin2) Control Peptide |
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| Description | Highly purified. Control Peptide for A0575 (affinity purified antibody) and A0575-01 (antiserum). Tissue acidosis that occurs in ischemia, tissue damage or inflammation is accompanied by pain. Proton-gated cation channels are activated by low pH in nociceptive neurons. H+-gated channels are members of the NaC/DEG superfamily that include: (1) Amiloride-sensitive epithelial Na+ channels (a, b, g, and d-ENaC subunits); (2) A FMRFamide-gated channel (FaNaC); (3) mechanosensory channel proteins of nematode degenerins (DEG). NaC/DEG superfamily is characterized by intracellular N and C-termini, two transmembrane domains, and a large extracellular loop. All members of this family are selective for Na+ and blocked by amiloride. The mammalian homolog of degenerins (MDEG or MDEG1) is now designated ASIC for Acid Sensing Ion Channels). There are at least three distinct proteins in ASIC family. ASIC1 is identical with human BNAC2 or BNC2. It is expressed in brain and dorsal root ganglions (DRG) c |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A0574-02 |
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| Order / More Info | Acid Sensitive Ion Channel 2b, Rat (ASIC2B, MDEG2, Mammalian Degenerin2) Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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