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| Product Name | AVE-1625 |
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| Description | Purity >98%. The central cannabinoid (CB1 ) receptor is a G protein-coupled receptor that is widely distributed in the central nervous system and several peripheral tissues and binds the active component of cannabis, Delta9 -tetrahydrocannabinol. Signaling through the CB1 receptor is implicated in attentional and working memory deficits as well as obesity. AVE-1625 is a highly potent, selective antagonist for the CB1 receptor with Ki values of 0.16-0.44 nM. At 1-3 mg/kg, AVE-1625 significantly improves the performance of rodents in working memory tasks. At 30 mg/kg, AVE-1625 reduces caloric intake by more than 50% of controls and significantly increases lipolysis from fat tissues and reduces hepatic glycogen levels in rodents. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[1-[bis (4-chlorophenyl)methyl]-3-azetidinyl]-N-(3,5-difluorophenyl)-methanesulfonamide, Drinabant |
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| Gene, Accession, CAS # | CAS: 358970-97-5 |
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| Catalog # | LS-H6674 |
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| Order / More Info | AVE-1625 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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