| 产品详情 |
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| Product Name | RARRES2, Recombinant, Human, aa21-157, His-Tag (Retinoic Acid Receptor Responder Protein 2) |
| Description | Purity ~85% (SDS-PAGE). Adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chokine-like receptor 1 (CMKLR1). Its other ligands include G protein-coupled receptor 1 (GPR1) and chokine receptor-like 2 (CCRL2). Positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue. Also acts as a proinflammatory adipokine, causing an increase in secretion of proinflammatory and prodiabetic adipokines, which further impair adipose tissue metabolic function and have negative systic effects including impaired insulin sensitivity, altered glucose and lipid metabolism, and a decrease in vascular function in other tissues. Can have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases. Acts as a chotactic factor for le |
| Size | 50ug, 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | SwissProt: Q99969 |
| Catalog # | 370777 |
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| Order / More Info | RARRES2, Recombinant, Human, aa21-157, His-Tag (Retinoic Acid Receptor Responder Protein 2) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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