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| Product Name | UBE1C, Recombinant, Human, aa1-463, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). UBA3, also known as NEDD8-activating enzyme E1 catalytic subunit, is the catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Source: Recombinant corresponding to aa1-463 from human UBA3, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~54.4kD (487aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMADGEE PERKRRRIEE LLAEKMAVDG GCGDTGDWEG RWNHVKKFLE RSGPFTHPDF EPSTESLQFL LDTCKVLVIG AGGLGCELLK NLALSGFRQI HVIDMDTIDV SNLNRQFLFR PKDIGRPKAE VAAEFLNDRV PNCNVVPHFN KIQDFNDTFY RQFHIIVCGL DSIIARRWIN GMLISLLNYE DGVLDPSSIV PLIDGGTEGF KGNARVILPG MTACIECTLE LYPPQVNFPM CTIASMPRLP EHCIEYVRML QWPKEQPFGE GVPLDGDDPE HIQWIFQKSL ERASQYNIRG VTYRLTQGVV KRIIPAVAST NAVIAAVCAT EVFKIATSAY IPLNNYLVFN DVDGLYTYTF EA |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | UBE1C, Recombinant, Human, aa1-463, His-Tag (NEDD8-activating Enzyme E1 Catalytic Subunit, NEDD8-activating Enzyme E1C, Ubiquitin-activating Enzyme E1C, Ubiquitin-like Modifier-activating Enzyme 3, Ubiquitin-activating Enzyme 3, UBA3) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45470 |
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| Order / More Info | UBE1C, Recombinant, Human, aa1-463, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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