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| Product Name | Retinoblastoma, Recombinant, Human, His-Tag, aa773-928 (Rb) |
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| Description | Puri?ed using Ni 2+-NTA agarose. Purity ~90% (SDS-PAGE and Coomassie blue staining). Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases. The retinoblastoma gene RB was the first tumor suppressor gene cloned, and is a negative regulator of the cell cycle through its ability to bind the transcription factor E2F (MIM 189971) and repress transcription of genes required for S phase (Hanahan and Weinberg, 2000 [PubMed 10647931]).[supplied by OMIM] Source: Recombinant fusion protein containing the C-terminal fragment (residues 773-928) of human retinoblastoma protein (Rb) with an N-terminal His6-tag, expressed in E. coli. Application: Suitable for use in Kinase Assay. |
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| Size | 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P06400 |
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| Catalog # | R1660-02 |
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| Order / More Info | Retinoblastoma, Recombinant, Human, His-Tag, aa773-928 (Rb) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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