产品名称 Equine IL2 Antibody from CREATIVE DIAGNOSTICS
产品货号 CABT-L142
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE DIAGNOSTICS
产品概述
产品详情
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Antigenic SpecificityEquine IL2
Clonepolyclonal
Host SpeciesGoat
Reactive Speciesequine
Isotypen/a
Formatbiotin conjugate
Sizen/a
Concentrationn/a
ApplicationsELISA(Det), ICC/IF, WB
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DescriptionGoat Anti-Equine IL2 polyclonal antibody for ELISA(Det), ICC/IF, WB. Interleukin 2 was initially identified as a T cell growth factor that is produced by T cells following activation by mitogens or antigens. IL-2 has since been found to also stimulate the growth and differentiation of B cells, natural killer (NK) cells, lymphocyte activated killer (LAK) cells, monocytes/macrophages and oligodendrocytes. The biological activity of IL-2 is mediated by the binding of IL-2 to cell surface receptor complexes. The functional high-affinity receptor that mediate IL-2 signals is composed of three polypeptide chains, the IL-2 receptor alpha, beta b and gamma subunits. IL-2 also signals via the intermediate affinity receptor complex of the beta b and gamma subunits. In T cells, the beta b and gamma subunits are shared with the IL-15 receptor complex. The gamma subunit of the IL-2 receptor complex has also been shown to be a subunit of the receptor complexes of IL-4, IL-7, IL-9 and IL-21. At the amino acid sequence level, equine IL-2 shares 72%, 70%, 56% and 54% sequence similarities with human, porcine, rat and mouse IL-2, respectively. It has been reported that equine IL-2 augmented proliferation in equine peripheral blood mononuclear cells, but has no effect on mouse CTLL-2 cells.
ImmunogenRecombinant Protein
Other Namesn/a
Gene, Accession #Gene ID: 100034204, UniProt: P37997
Catalog #CABT-L142
Price
Order / More InfoEquine IL2 Antibody from CREATIVE DIAGNOSTICS
Product Specific Referencesn/a
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