| 产品详情 |
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| Product Name | AZ-6102 |
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| Description | MW: 428.54. Purity ≥98% by HPLC. AZ-6102 is a potent TNKS1/2 inhibitor (Tankyrase) that displays >100-fold selectivity against other poly (ADP-ribose) polymerase (PARP) family enzymes and inhibits Wnt pathway with IC50 value of 5 nM in DLD-1 cells. Inhibition of the PARP catalytic domain of the tankyrases is known to inhibit the Wnt pathway via increased stabilization of Axin. Wnt pathway plays important role in cancer; tissue homeostasis; germline mutations of various Wnt pathway components |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [2- (4- (6- ( (3R; 5S)-3; 5-dimethylpiperazin-1-yl)-4-methylpyridin-3-yl) phenyl)-7-methyl-3; 7-dihydro-4H-pyrrolo[2; 3-d]pyrimidin-4-one] |
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| Gene, Accession, CAS # | CAS: 1645286-75-4 |
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| Catalog # | MBS846342 |
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| Order / More Info | AZ-6102 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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