| 产品详情 |
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| Antigenic Specificity | Human AXIN1 |
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| Clone | U.729.3 |
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| Host Species | Rabbit |
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| Reactive Species | human, nonhuman primate |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC-P, IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human AXIN1 monoclonal antibody for IHC-P, IP, WB. This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. |
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| Immunogen | Recombinant Protein |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 8312, UniProt: O15169 |
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| Catalog # | CABT-L1205 |
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| Price | |
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| Order / More Info | Human AXIN1 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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