| 产品详情 |
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| Product Name | SC-51322 |
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| Description | Purity >98%. The prostaglandin E2 (PGE2 ) receptor (EP1 ) is involved in triggering PGE2 -mediated pain as well as neuronal survival and growth. SC-51322 is a selective EP1 antagonist that inhibits PGE2 signaling in a guinea pig ileum muscle strip assay with a pA2 value of 8.1 and demonstrates analgesic activity in a mouse writhing assay with an ED50 value of 0.9 mg/kg. It is pharmacologically similar to SC-51089, but does not release hydrazine, a known carcinogen to rats, as does SC-51089. SC-51322 potentiates the vasorelaxation of human pulmonary vein induced by PGE2 with an EC50 value of 7.75 µM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 8-chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]hydrazide, dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid |
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| Gene, Accession, CAS # | CAS: 146032-79-3 |
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| Catalog # | LS-H9866 |
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| Order / More Info | SC-51322 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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