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| Product Name | Neurotensin, Human |
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| Description | Purified ≥ 90% by HPLC. 13 aa and NT8-13 were synthesized using standard fmoc amino acids and purified >90-100% by hplc. Neurotensin (NT) is an endogenous tridecapeptide neurotransmitter (pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-pro-Tyr-Ile-Leu-OH) that was originally isolated from bovine hypothalamus. NT influences distinct central and peripheral physiological functions in mammals. Central administration of NT modulates dopaminergic transmission and triggers hypothermic and naloxone-insensitive analgesic responses, whereas peripheral effects include hypotension, decrease gastric acid release, potentiation of lipid digestion. NT causes contraction of smooth muscle. NT is widely distributed throughout the CNS. It has been localized to catecholamine-containing neurons. NT gene (human chromosome 12q21) produces both NT and neuromedin N (NN). In the rat, the NT precursor consists of a 169-aa polypeptide. The signal peptide (1-22 aa) is removed to produce a peptide that is further processed to |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Neurotensin, Human (Human Proneurotensin, Large Neuromedin N, Neuromedin N Preproprotein, NMN-125, NN, NT, NT/N, NTRH, NTS, NTS1, Proneuromedin N mRNA, Tail Peptide) (Control Peptide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N2177-02 |
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| Order / More Info | Neurotensin, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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