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| Product Name | Bone Morphogenetic Protein 4, 293-408aa, Recombinant, Human (BMP4, DVR4) |
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| Description | Purity ≥ 95% by SDS-PAGE. Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-β superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Endotoxin Level: ≤ 1.0 EU per 1 ug of protein (determined by LAL method)15% SDS-PAGE (3ug) Molecular Weight: 13.2kD (117 aa) AA Sequences: MSPKHHSQRA RKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SM |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001193 |
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| Catalog # | B2553-21A |
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| Order / More Info | Bone Morphogenetic Protein 4, 293-408aa, Recombinant, Human (BMP4, DVR4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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