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| Product Name | Recombinant Human Vascular cell adhesion protein 1 |
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| Description | 25-698aa; Extracellular Domain. MW: 90.2kD. Purity >90% as determined by SDS-PAGE. Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte igration to sites of inflammation. |
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| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [INCAM-100; CD106] |
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| Gene, Accession, CAS # | VCAM1, Gene ID: 7412, Accession: NP_001069.1 |
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| Catalog # | MBS949714 |
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| Order / More Info | Recombinant Human Vascular cell adhesion protein 1 from MYBIOSOURCE INC. |
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| Product Specific References | Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.Osborn L., Hession C., Tizard R., Vassallo C., Luhowskyj S., Chi-Rosso G., Lobb R.Cell 59:1203-1211(1989) Full length vascular cell adhesion molecule 1 (VCAM-1).Polte T., Newman W., Gopal T.V.Nucleic Acids Res. 18:5901-5901(1990) Cloning of an alternate form of vascular cell adhesion molecule-1 (VCAM1).Hession C., Tizard R., Vassallo C., Schiffer S.B., Goff D., Moy P., |
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