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| Product Name | IL-17 (IL-17A), Recombinant, Mouse (IL-17, CTLA-8) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. Endotoxin:≤0.1ng/ug of protein (≤1EU/ug). The originally described IL-17 protein, now known as IL-17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules.Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles.The six known members of this family, IL-17A through IL-17F, are secreted as homodimers.IL-17A exhibits cross-species bioactivity between human and murine cells.Recombinant murine IL-17A is a 30.0kD disulfide-linked homodimer of two 133 amino acid polypeptide chains. Biological Activity: Measured by its ability to induce IL-6 production by NIH 3T3 cells. AA Sequence: AAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLI |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143387 |
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| Order / More Info | IL-17 (IL-17A), Recombinant, Mouse (IL-17, CTLA-8) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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