| 产品详情 |
| Edit |   |
|---|
| Product Name | IL-12/IL-23 ELISA (p40) |
|---|
| Description | Biologically active IL-12 is a disulfide-linked heterodimeric 70-kDa cytokine composed of a 35-kDa (p35) and a 40-kDa (p40) subunit. P35, a member of the IL-6 superfamily, is secreted in response to IFN gamma and agonists of TLR3, 4, or 7. However, p35 expression has been shown to be inhibited by Th2 cytokines and expressed at much lower levels than p40. Expression of p40 is regulated independently of p35. Moreover, p40 has been shown to be secreted as either a monomer or homodimer. Although each subunit alone does not possess IL-12 bioactivity, the p40 homodimer can bind to the IL-12 receptor and act as an antagonist to IL-12 p70. The receptor for this cytokine is composed of two subunits, IL-12R beta 1 and IL-12R beta 2, the latter of which is the signaling component of the receptor. Sample Types: Human cell culture, citrate plasma, heparin plasma, serum. Sample Size: 50 µL. Range: 31.3 - 2,000 pg/mL. Sensitivity: < 10 pg/mL. Time: 4hr 10min |
|---|
| Size | 96 wells |
|---|
| Concentration | n/a |
|---|
| Applications | Immunoassays. Research Use Only. Not for Use in Diagnostic Procedures. |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 61-ILPHU-E01 |
|---|
| Price | |
|---|
| Order / More Info | IL-12/IL-23 ELISA (p40) from ALPCO |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|