产品名称 IL-12/IL-23 p40, BioAssay™ ELISpot Kit (Human) from UNITED STATES BIOLOGICAL
产品货号 167661
产品价格 现货询价,电话:010-67529703
产品规格 96 tests
产品品牌 UNITED STATES BIOLOGICAL
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Product NameIL-12/IL-23 p40, BioAssay™ ELISpot Kit (Human)
DescriptionInterleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40kD (p40) subunit and a 35kD (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells. Intended Use: For the quantitative determination of the frequency of cells releasing human IL-12/IL-23 p40. Test Principle: The enzyme-linked immunospot (ELISpot) assay was originally developed for the detection of individual B cells secreting antigen-specific antibodies (31, 32). This method has since been adapted for the detection of individual cells secreting specific cytokines or
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Catalog #167661
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