| 产品详情 |
| Edit |   |
|---|
| Product Name | IL-12/IL-23 p40, ELISpot BioAssay™ Kit (Canine) |
|---|
| Description | Canine IL-12/IL-23 p40 is a 40kD glycoprotein that shows considerable structural similarity to the extracellular domain of hematopoietin receptors. It is synthesized as a 329aa precursor with a 22 aa signal sequence and a 307 aa mature region. It contains one 90 aa fibronectin type III domain and one 75 aa Ig C2-like region. There are two intrachain disulfide bonds and two potential N-linked glycosylation sites. p40 is an inducible molecule synthesized in response to APC-activating substances such as LPS and CpG. Once made, it can be secreted as a monomer, homodimer, heterodimer linked to p35 (IL-12), and a heterodimer linked to p19 (IL-23). Relative to p35, it exists in a 10-1000 fold excess. Canine p40 is 94%, 85%, 84%, 65%, and 65% aa identical to feline, human, porcine, rat and mouse p40, respectively. Cells known to express p40 include macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, plasmacytoid dendritic cells, and microglia. p40 binds to th |
|---|
| Size | 1 kit |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | IL-12/IL-23 p40, ELISpot BioAssay™ Kit (Canine) (IL-12, IL-23 p40, Interleukin-12 Subunit beta, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40kD Subunit, CLMF p40, IL-12 Subunit p40, IL12B) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | I8434-30H1 |
|---|
| Price | |
|---|
| Order / More Info | IL-12/IL-23 p40, ELISpot BioAssay™ Kit (Canine) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|