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| Product Name | DNMT3B, Active |
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| Description | Full Length. MW: ~138 kDa. Description: Recombinant full-length human DNMT3B was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: DNMT3B or DNA (cytosine-5-)-methyltransferase 3 beta encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. DNMT3B can methylate unmethylated and hemimethylated DNA with equal efficiencies (1). DNMT3B localizes primarily to the nucleus and its expressi |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Methyltransferase Assay |
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| Other Names | [Synthetic construct Homo sapiens clone IMAGE:40080753, MGC:133466 DNMT3B protein (DNMT3B) mRNA, encodes complete protein; DNA (cytosine-5)-methyltransferase 3B; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase HsaIIIB; DNA MTase HsaIIIB; M.HsaIIIB] |
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| Gene, Accession, CAS # | DNMT3B, Gene ID: 1789, Accession: BC111933 |
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| Catalog # | MBS515488 |
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| Order / More Info | DNMT3B, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Yanagisawa, Y. et al: The human DNA methyltransferases DNMT3A and DNMT3B have two types of promoters with different CpG contents. Biochim. Biophys. Acta 1577: 457-465, 2002. 2. Okano, M. et al: DNA methyltransferase Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99: 247-257, 1999. |
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