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| Product Name | Glucagon-Like Peptide 1, Human (aa7-37) (GLP-1, GLP1) |
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| Description | Purity ~95% (RP-HPLC). Glucagon is a member of a multigene family comprising of Secretin, Vasoactive Intestinal Peptide (VIP), Gastric Inhibitory Peptide (GIP) and others like Glicentin and Oxyntomodulin (OXM), which differs from glucagon by C- terminal octapeptide. The glucagon precursor contains at least 3 intervening sequences that divide the protein- coding portion into 4 regions corresponding to the signal peptide and part of the N-terminal peptide, the remainder of the N-terminal peptide and glucagon, glucagon-like peptide-1 (GLP1), and GLP2. The GLP 1 & 2 stimulates intestinal growth and up regulates villus height in the small intestine, concomitant with increased crupt cell proliferation and decreased enterocyte apoptosis. The two GLP's are mainly produced in the A cells of the Islets of Langerhans in response to a drop in blood sugar concentration. GLP1, a processed active peptide of 30aa (chr 2q36-q37) is a potent insulin secretagogue, plays a major role in the enteroinsular |
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| Size | 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | G2040-36J |
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| Order / More Info | Glucagon-Like Peptide 1, Human (aa7-37) (GLP-1, GLP1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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