| Edit |   |
| Antigenic Specificity | ErbB4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | n/a |
| Size | 0.05 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Paraffin* |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RABBIT ANTI HUMAN ErbB4. This item detects an epitope within the internal region of human ErbB4, a transmembrane protein which is a member of the epidermal growth factor receptor subfamily. ErbB4 is activated by a number of factors including neuregulins and betacellulin, which leads to the cleavage of a 120kD ectodomain fragment by TACE. In the cell, the remaining 80kD fragment of ErbB4 is internalised and cleaved by gamma-secretase. This fragment translocates to the nucleus and induces cell pro |
| Immunogen | Synthetic peptide: Internal domain of human ErbB4.Histology Positive Control Tissue: Glomerulus |
| Other Names | receptor tyrosine-protein kinase erbB-4 isoform JM-a/CVT-2; Receptor tyrosine-protein kinase erbB-4; receptor tyrosine-protein kinase erbB-4; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; human epidermal growth factor receptor 4; proto-oncogene-like protein c-ErbB-4; tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4; erb-b2 receptor tyrosine kinase 4; Prot |
| Gene, Accession # | ErbB4, Gene ID: 2066, NCBI: NP_001036064.1, UniProt: Q15303 |
| Catalog # | MBS221421 |
| Price | |
| Order / More Info | ErbB4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |